Persistent problems with Magic Mouse

Here is more information in case it's helpful:

• I plugged in a wired Logitech mouse, and to my surprise, it also doesn't work. I thought the issue was related to the wireless/Bluetooth connection, but it's clearly not.
• I have a Wacom tablet connected to my computer, and it works fine—regardless of whether it's connected wirelessly (via USB dongle) or wired (via USB).

It seems to be something wrong with whatever system/software specifically controls the mouse.

Thanks for your response. I need to update my profile; I'm already on 10.11.6. I've tried removing the Wacom tablet from the room, and even completely uninstalling it, but that doesn't have any effect.

Well, hate to say this, but it seems it may be the Wacom tablet. When I removed it previously I had only unplugged the tablet from the computer; I didn't remove the radio transmitter inside.

This time I unplugged the USB cable and removed the radio dongle, and so far I haven't had a mouse disconnect. I can't be certain that is the problem yet, because I've had 24-48 hour (or even longer) periods where the mouse worked when the tablet was connected. But it's looking like that *could* be the issue.

It's a Magic Mouse 2.

Well, the bummer is that I need both. I use the tablet for photography work, and I use the mouse for other stuff. Too bad. I'm hoping that if I plug the tablet in via USB and don't use the radio dongle it may not interfere.

I guess it must be to transmit input to the tablet. However, I was referring to the tablet itself, which can be connected via USB or via USB radio/wireless dongle.

Just reporting back. The problem is definitely the Wacom tablet. I first unplugged the tablet from the computer, removed the wireless transmitter inside of the tablet (that enables wireless mode), and removed the USB radio dongle from the computer, and restarted. The mouse worked fine. It continued to work for 2 days without a freeze.

This morning I plugged the tablet back into the iMac via USB, and did not reconnect the wireless transmitter inside of the tablet, or plug in the USB radio dongle. I was hoping that the tablet wouldn't cause interference when it was plugged into the iMac directly via USB. No such luck. It worked fine for a few hours, but after waking the iMac from sleep just now, the mouse froze. I can use the tablet (both the pen, and my finger) to move the cursor on the screen, but moving the mouse won't move the cursor. Clicking the mouse button does register input, but that's about all I can do with the mouse.

This is frustrating because I need to use both the tablet and mouse for my work. I guess I'll contact Wacom.

Yes, that's what's strange. I have two bluetooth Apple keyboards and the Wacom tablet doesn't interfere with them.